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TitleIn silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.
Journal, issue, pagesFront Immunol, Vol. 11, Page 1824-1824, Year 2020
Publish dateDec 19, 2019 (structure data deposition date)
AuthorsWinter, P. / Stubenvoll, S. / Scheiblhofer, S. / Joubert, I.A. / Strasser, L. / Briganser, C. / Soh, W.T. / Hofer, F. / Kamenik, A.S. / Dietrich, V. ...Winter, P. / Stubenvoll, S. / Scheiblhofer, S. / Joubert, I.A. / Strasser, L. / Briganser, C. / Soh, W.T. / Hofer, F. / Kamenik, A.S. / Dietrich, V. / Michelini, S. / Laimer, J. / Lackner, P. / Horejs-Hoeck, J. / Tollinger, M. / Liedl, K.R. / Brandstetter, J. / Huber, C.G. / Weiss, R.
External linksFront Immunol / PubMed:33013833
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-6trk:
Phl p 6 fold stabilized mutant - S46Y
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • phleum pratense (timothy grass)
KeywordsALLERGEN / Phleum pratense / grass pollen allergen / stabilized fold mutant / Phl p 6

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