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TitleStructural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Journal, issue, pagesNat Commun, Vol. 11, Page 4931-4931, Year 2020
Publish dateApr 13, 2020 (structure data deposition date)
AuthorsYang, S.W. / Huang, X. / Lin, W. / Min, J. / Miller, D.J. / Mayasundari, A. / Rodrigues, P. / Griffith, E.C. / Gee, C.T. / Li, L. ...Yang, S.W. / Huang, X. / Lin, W. / Min, J. / Miller, D.J. / Mayasundari, A. / Rodrigues, P. / Griffith, E.C. / Gee, C.T. / Li, L. / Li, W. / Lee, R.E. / Rankovic, Z. / Chen, T. / Potts, P.R.
External linksNat Commun / PubMed:33004795
MethodsX-ray diffraction
Resolution2.19 Å
Structure data

PDB-6wjh:
Crystal structure of MAGE-A11 bound to the PCF11 degron
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / MAGE-A11 / PCF 11 / ubiquitin ligase / protein complex

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