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TitleCharacterization of tau binding by gosuranemab.
Journal, issue, pagesNeurobiol. Dis., Vol. 146, Page 105120-105120, Year 2020
Publish dateJul 26, 2019 (structure data deposition date)
AuthorsSopko, R. / Golonzhka, O. / Arndt, J. / Quan, C. / Czerkowicz, J. / Cameron, A. / Smith, B. / Murugesan, Y. / Gibbons, G. / Kim, S.J. ...Sopko, R. / Golonzhka, O. / Arndt, J. / Quan, C. / Czerkowicz, J. / Cameron, A. / Smith, B. / Murugesan, Y. / Gibbons, G. / Kim, S.J. / Trojanowski, J.Q. / Lee, V.M.Y. / Brunden, K.R. / Graham, D.L. / Weinreb, P.H. / Hering, H.
External linksNeurobiol. Dis. / PubMed:32991997
MethodsX-ray diffraction
Resolution1.556 Å
Structure data

PDB-6pxr:
Anti-TAU BIIB092 FAB with TAU peptide
Method: X-RAY DIFFRACTION / Resolution: 1.556 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TAU / antibody / BIIB092 / gosuranemab tau complex

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