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Structure paper

TitleStructural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Journal, issue, pagesNucleic Acids Res., Vol. 48, Page 9969-9985, Year 2020
Publish dateJan 23, 2020 (structure data deposition date)
AuthorsOsz, J. / McEwen, A.G. / Bourguet, M. / Przybilla, F. / Peluso-Iltis, C. / Poussin-Courmontagne, P. / Mely, Y. / Cianferani, S. / Jeffries, C.M. / Svergun, D.I. / Rochel, N.
External linksNucleic Acids Res. / PubMed:32974652
MethodsX-ray diffraction
Resolution2.1 - 2.4 Å
Structure data

PDB-6xwg:
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-6xwh:
Crystal Structure of the Human RXR DNA-Binding Domain Homodimer Bound to the Human Hoxb13 DR0 Response Element
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Protein-DNA complex / Nuclear Receptor

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