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TitleDimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.
Journal, issue, pagesBiochemistry, Vol. 59, Page 3982-3992, Year 2020
Publish dateJun 4, 2020 (structure data deposition date)
AuthorsLiau, N.P.D. / Venkatanarayan, A. / Quinn, J.G. / Phung, W. / Malek, S. / Hymowitz, S.G. / Sudhamsu, J.
External linksBiochemistry / PubMed:32970425
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-6xag:
Apo BRAF dimer bound to 14-3-3
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/Transferase / Kinase / SIGNALING PROTEIN / SIGNALING PROTEIN-Transferase complex

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