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TitleSelective Affimers Recognise the BCL-2 Family Proteins BCL-x L and MCL-1 through Noncanonical Structural Motifs*.
Journal, issue, pagesChembiochem, Vol. 22, Page 232-240, Year 2021
Publish dateSep 9, 2019 (structure data deposition date)
AuthorsMiles, J.A. / Hobor, F. / Trinh, C.H. / Taylor, J. / Tiede, C. / Rowell, P.R. / Jackson, B.R. / Nadat, F.A. / Ramsahye, P. / Kyle, H.F. ...Miles, J.A. / Hobor, F. / Trinh, C.H. / Taylor, J. / Tiede, C. / Rowell, P.R. / Jackson, B.R. / Nadat, F.A. / Ramsahye, P. / Kyle, H.F. / Wicky, B.I.M. / Clarke, J. / Tomlinson, D.C. / Wilson, A.J. / Edwards, T.A.
External linksChembiochem / PubMed:32961017
MethodsX-ray diffraction
Resolution1.79 - 2.2 Å
Structure data

PDB-6st2:
Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-6stj:
Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / Affimer

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