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Structure paper

TitleElucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Journal, issue, pagesNat Commun, Vol. 11, Page 4744-4744, Year 2020
Publish dateApr 30, 2020 (structure data deposition date)
AuthorsYoshida, H. / Park, S.Y. / Sakashita, G. / Nariai, Y. / Kuwasako, K. / Muto, Y. / Urano, T. / Obayashi, E.
External linksNat Commun / PubMed:32958768
MethodsX-ray diffraction
Resolution3.02 - 3.35 Å
Structure data

PDB-7c06:
Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

PDB-7c07:
Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA.
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-7c08:
Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Method: X-RAY DIFFRACTION / Resolution: 3.35 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • schizosaccharomyces pombe 972h- (yeast)
  • synthetic construct (others)
KeywordsSPLICING/RNA / pre-mRNA / splicing / intron / 3' splice site / zinc-finger / SPLICING-RNA complex

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