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TitleBiochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii .
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 16545-16561, Year 2020
Publish dateOct 24, 2019 (structure data deposition date)
AuthorsLiu, T. / Abboud, M.I. / Chowdhury, R. / Tumber, A. / Hardy, A.P. / Lippl, K. / Lohans, C.T. / Pires, E. / Wickens, J. / McDonough, M.A. ...Liu, T. / Abboud, M.I. / Chowdhury, R. / Tumber, A. / Hardy, A.P. / Lippl, K. / Lohans, C.T. / Pires, E. / Wickens, J. / McDonough, M.A. / West, C.M. / Schofield, C.J.
External linksJ. Biol. Chem. / PubMed:32934009
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-6t8m:
Prolyl Hydroxylase (PHD) involved in hypoxia sensing by Dictyostelium discoideum
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-GOL:
GLYCEROL

ChemComp-OGA:
N-OXALYLGLYCINE / inhibitor*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • dictyostelium discoideum (eukaryote)
KeywordsOXIDOREDUCTASE / Prolyl Hydroxylase / Oxygen Sensing / 2-oxoglutarate and iron dependent oxygenase

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