Movie
Controller
Structure viewers
About Yorodumi Papers
+Search query
-Structure paper
| Title | Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 63, Page 14530-14559, Year 2020 |
| Publish date | Jul 7, 2020 (structure data deposition date) |
 Authors | Scott, J.S. / Moss, T.A. / Balazs, A. / Barlaam, B. / Breed, J. / Carbajo, R.J. / Chiarparin, E. / Davey, P.R.J. / Delpuech, O. / Fawell, S. ...Scott, J.S. / Moss, T.A. / Balazs, A. / Barlaam, B. / Breed, J. / Carbajo, R.J. / Chiarparin, E. / Davey, P.R.J. / Delpuech, O. / Fawell, S. / Fisher, D.I. / Gagrica, S. / Gangl, E.T. / Grebe, T. / Greenwood, R.D. / Hande, S. / Hatoum-Mokdad, H. / Herlihy, K. / Hughes, S. / Hunt, T.A. / Huynh, H. / Janbon, S.L.M. / Johnson, T. / Kavanagh, S. / Klinowska, T. / Lawson, M. / Lister, A.S. / Marden, S. / McGinnity, D.F. / Morrow, C.J. / Nissink, J.W.M. / O'Donovan, D.H. / Peng, B. / Polanski, R. / Stead, D.S. / Stokes, S. / Thakur, K. / Throner, S.R. / Tucker, M.J. / Varnes, J. / Wang, H. / Wilson, D.M. / Wu, D. / Wu, Y. / Yang, B. / Yang, W. |
 External links | J. Med. Chem. / PubMed:32910656 |
| Methods | X-ray diffraction |
| Resolution | 1.8 - 2 Å |
| Structure data |  PDB-6zoq:  PDB-6zor:  PDB-6zos: |
| Chemicals |  ChemComp-QNE:  ChemComp-HOH:  ChemComp-QNH:  ChemComp-QNK: |
| Source |
|
 Keywords | GENE REGULATION / oestrogen receptor |
homo sapiens (human)