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TitleIdentification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 17922-17934, Year 2020
Publish dateMay 25, 2020 (structure data deposition date)
AuthorsBusch, J.M.C. / Matsoukas, M.T. / Musgaard, M. / Spyroulias, G.A. / Biggin, P.C. / Vakonakis, I.
External linksJ. Biol. Chem. / PubMed:32873708
MethodsX-ray diffraction
Resolution1.46 Å
Structure data

PDB-6z4a:
Structure of the human SAS-6 N-terminal domain, F131E mutant
Method: X-RAY DIFFRACTION / Resolution: 1.46 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / centrosome / centriole / cartwheel / alpha/beta protein

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