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-Structure paper
Title | Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. |
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Journal, issue, pages | Nat Commun, Vol. 11, Page 4282-4282, Year 2020 |
Publish date | May 2, 2020 (structure data deposition date) |
![]() | Vuong, W. / Khan, M.B. / Fischer, C. / Arutyunova, E. / Lamer, T. / Shields, J. / Saffran, H.A. / McKay, R.T. / van Belkum, M.J. / Joyce, M.A. ...Vuong, W. / Khan, M.B. / Fischer, C. / Arutyunova, E. / Lamer, T. / Shields, J. / Saffran, H.A. / McKay, R.T. / van Belkum, M.J. / Joyce, M.A. / Young, H.S. / Tyrrell, D.L. / Vederas, J.C. / Lemieux, M.J. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 2 Å |
Structure data | ![]() PDB-6wtj: ![]() PDB-6wtk: ![]() PDB-6wtm: |
Chemicals | ![]() ChemComp-K36: ![]() ChemComp-HOH: ![]() ChemComp-UED: |
Source |
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![]() | Hydrolase/Hydrolase Inhibitor / COVID-19 / SARS-CoV-2 / 3CLpro / coronavirus / main protease / kinetics / SARS / VIRAL PROTEIN / Hydrolase-Hydrolase Inhibitor complex |