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TitleFunctional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Journal, issue, pagesFront Immunol, Vol. 11, Page 1504-1504, Year 2020
Publish dateMay 29, 2020 (structure data deposition date)
AuthorsLaursen, N.S. / Pedersen, D.V. / Gytz, H. / Zarantonello, A. / Bernth Jensen, J.M. / Hansen, A.G. / Thiel, S. / Andersen, G.R.
External linksFront Immunol / PubMed:32849513
MethodsX-ray diffraction
Resolution2.19 Å
Structure data

PDB-6z6v:
Globular head of C1q in complex with the nanobody C1qNb75
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsIMMUNE SYSTEM / complement / antibody / nanobody / C1q

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