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TitlePentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37-Viruses That Cause Highly Contagious Eye Infections.
Journal, issue, pagesAcs Chem. Biol., Vol. 15, Page 2683-2691, Year 2020
Publish dateDec 20, 2019 (structure data deposition date)
AuthorsJohansson, E. / Caraballo, R. / Mistry, N. / Zocher, G. / Qian, W. / Andersson, C.D. / Hurdiss, D.L. / Chandra, N. / Thompson, R. / Frangsmyr, L. ...Johansson, E. / Caraballo, R. / Mistry, N. / Zocher, G. / Qian, W. / Andersson, C.D. / Hurdiss, D.L. / Chandra, N. / Thompson, R. / Frangsmyr, L. / Stehle, T. / Arnberg, N. / Elofsson, M.
External linksAcs Chem. Biol. / PubMed:32845119
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-6tsd:
Crystal structure of human coxsackievirus A24v in complex with pentavalent inhibitor ME0752
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-HEZ:
HEXANE-1,6-DIOL

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • coxsackievirus a24
KeywordsVIRUS / human Coxsackievirus A24v / starfish-like inhibitor / pentavelent

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