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TitleIdentification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy.
Journal, issue, pagesSignal Transduct Target Ther, Vol. 5, Page 158-158, Year 2020
Publish dateMay 29, 2020 (structure data deposition date)
AuthorsLiu, H. / Bi, X. / Zhou, Y. / Shi, R. / Yao, S. / Qi, J. / Feng, H. / Feng, M. / Yan, J. / Tan, S.
External linksSignal Transduct Target Ther / PubMed:32839442
MethodsX-ray diffraction
Resolution1.997 Å
Structure data

PDB-7c88:
Complex structure of JS003 and PD-L1
Method: X-RAY DIFFRACTION / Resolution: 1.997 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / PD-L1 / antibody / pH

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