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TitleDesigned protein logic to target cells with precise combinations of surface antigens.
Journal, issue, pagesScience, Vol. 369, Page 1637-1643, Year 2020
Publish dateJul 20, 2020 (structure data deposition date)
AuthorsLajoie, M.J. / Boyken, S.E. / Salter, A.I. / Bruffey, J. / Rajan, A. / Langan, R.A. / Olshefsky, A. / Muhunthan, V. / Bick, M.J. / Gewe, M. ...Lajoie, M.J. / Boyken, S.E. / Salter, A.I. / Bruffey, J. / Rajan, A. / Langan, R.A. / Olshefsky, A. / Muhunthan, V. / Bick, M.J. / Gewe, M. / Quijano-Rubio, A. / Johnson, J. / Lenz, G. / Nguyen, A. / Pun, S. / Correnti, C.E. / Riddell, S.R. / Baker, D.
External linksScience / PubMed:32820060
MethodsX-ray diffraction
Resolution2.103 Å
Structure data

PDB-7jh5:
Co-LOCKR: de novo designed protein switch
Method: X-RAY DIFFRACTION / Resolution: 2.103 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsDE NOVO PROTEIN / Helical bundle / protein switch

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