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TitleSelective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains.
Journal, issue, pagesNat Commun, Vol. 11, Page 4115-4115, Year 2020
Publish dateDec 2, 2019 (structure data deposition date)
AuthorsLa Sala, G. / Michiels, C. / Kukenshoner, T. / Brandstoetter, T. / Maurer, B. / Koide, A. / Lau, K. / Pojer, F. / Koide, S. / Sexl, V. ...La Sala, G. / Michiels, C. / Kukenshoner, T. / Brandstoetter, T. / Maurer, B. / Koide, A. / Lau, K. / Pojer, F. / Koide, S. / Sexl, V. / Dumoutier, L. / Hantschel, O.
External linksNat Commun / PubMed:32807795
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-6tlc:
Unphosphorylated human STAT3 in complex with MS3-6 monobody
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Inhibitor / Complex / STAT3 / Monobody

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