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Structure paper

TitleParallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design.
Journal, issue, pagesCell Chem Biol, Vol. 27, Page 1241-1249.e4, Year 2020
Publish dateMay 14, 2020 (structure data deposition date)
AuthorsTran, B. / Pichling, P. / Tenney, L. / Connelly, C.M. / Moon, M.H. / Ferre-D'Amare, A.R. / Schneekloth Jr., J.S. / Jones, C.P.
External linksCell Chem Biol / PubMed:32795418
MethodsX-ray diffraction
Resolution3.2 - 3.23 Å
Structure data

PDB-6wzr:
Fusibacterium ulcerans ZTP riboswitch bound to p-1-pyridinyl AICA
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6wzs:
Fusibacterium ulcerans ZTP riboswitch bound to m-1-pyridinyl AICA
Method: X-RAY DIFFRACTION / Resolution: 3.23 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-UG1:
5-amino-1-(pyridin-4-yl)-1H-imidazole-4-carboxamide

ChemComp-HOH:
WATER

ChemComp-UG4:
5-amino-1-(pyridin-3-yl)-1H-imidazole-4-carboxamide

Source
  • fusobacterium ulcerans (bacteria)
KeywordsRNA / Riboswitch / pseudoknot / Purine Biosynthesis / AICAR

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