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Structure paper

TitleA high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.
Journal, issue, pagesJ. Exp. Med., Vol. 217, Year 2020
Publish dateOct 30, 2019 (structure data deposition date)
AuthorsThai, E. / Costa, G. / Weyrich, A. / Murugan, R. / Oyen, D. / Flores-Garcia, Y. / Prieto, K. / Bosch, A. / Valleriani, A. / Wu, N.C. ...Thai, E. / Costa, G. / Weyrich, A. / Murugan, R. / Oyen, D. / Flores-Garcia, Y. / Prieto, K. / Bosch, A. / Valleriani, A. / Wu, N.C. / Pholcharee, T. / Scally, S.W. / Wilson, I.A. / Wardemann, H. / Julien, J.P. / Levashina, E.A.
External linksJ. Exp. Med. / PubMed:32790871
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-6uud:
Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsIMMUNE SYSTEM / Malaria / Antibody

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