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TitlePapain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Journal, issue, pagesNature, Vol. 587, Page 657-662, Year 2020
Publish dateApr 28, 2020 (structure data deposition date)
AuthorsShin, D. / Mukherjee, R. / Grewe, D. / Bojkova, D. / Baek, K. / Bhattacharya, A. / Schulz, L. / Widera, M. / Mehdipour, A.R. / Tascher, G. ...Shin, D. / Mukherjee, R. / Grewe, D. / Bojkova, D. / Baek, K. / Bhattacharya, A. / Schulz, L. / Widera, M. / Mehdipour, A.R. / Tascher, G. / Geurink, P.P. / Wilhelm, A. / van der Heden van Noort, G.J. / Ovaa, H. / Muller, S. / Knobeloch, K.P. / Rajalingam, K. / Schulman, B.A. / Cinatl, J. / Hummer, G. / Ciesek, S. / Dikic, I.
External linksNature / PubMed:32726803
MethodsX-ray diffraction
Resolution3.18 Å
Structure data

PDB-6yva:
PLpro-C111S with mISG15
Method: X-RAY DIFFRACTION / Resolution: 3.18 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
  • mus musculus (house mouse)
KeywordsCELL INVASION / Deubiquitinase / papain-like-protease / SARS-CoV-2 / ISG15 / complex

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