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Structure paper

TitleStructural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Journal, issue, pagesAdv Sci, Vol. 7, Page 2000532-2000532, Year 2020
Publish dateOct 24, 2019 (structure data deposition date)
AuthorsChen, Z. / Li, Z. / Hu, X. / Xie, F. / Kuang, S. / Zhan, B. / Gao, W. / Chen, X. / Gao, S. / Li, Y. ...Chen, Z. / Li, Z. / Hu, X. / Xie, F. / Kuang, S. / Zhan, B. / Gao, W. / Chen, X. / Gao, S. / Li, Y. / Wang, Y. / Qian, F. / Ding, C. / Gan, J. / Ji, C. / Xu, X. / Zhou, Z. / Huang, J. / He, H.H. / Li, J.
External linksAdv Sci / PubMed:32714761
MethodsX-ray diffraction
Resolution1.8 - 3.1 Å
Structure data

PDB-6l5l:
Crystal structure of human DEAD-box RNA helicase DDX21 at apo state
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6l5m:
Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-6l5n:
Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state
Method: X-RAY DIFFRACTION / Resolution: 2.242 Å

PDB-6l5o:
Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-HOH:
WATER

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / apo / with AMP / RNA BINDING PROTEIN/RNA / RNA bound post-unwound state / RNA BINDING PROTEIN-RNA complex / ADP bound complex

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