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Structure paper

TitleTimeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
Journal, issue, pagesEmbo J., Vol. 39, Page e104185-e104185, Year 2020
Publish dateOct 28, 2019 (structure data deposition date)
AuthorsLerner, L.K. / Holzer, S. / Kilkenny, M.L. / Svikovic, S. / Murat, P. / Schiavone, D. / Eldridge, C.B. / Bittleston, A. / Maman, J.D. / Branzei, D. ...Lerner, L.K. / Holzer, S. / Kilkenny, M.L. / Svikovic, S. / Murat, P. / Schiavone, D. / Eldridge, C.B. / Bittleston, A. / Maman, J.D. / Branzei, D. / Stott, K. / Pellegrini, L. / Sale, J.E.
External linksEmbo J. / PubMed:32705708
MethodsX-ray diffraction / NMR (solution)
Resolution1.15 Å
Structure data

PDB-6t9q:
Crystal structure of the second, C-terminal repeat of the DNA-binding domain of human TImeless
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-6taz:
Timeless couples G quadruplex detection with processing by DDX11 during DNA replication
Method: SOLUTION NMR

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsREPLICATION / DNA-binding / 3-helix bundle / tandem repeat / DNA BINDING PROTEIN / DNA-binding protein

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