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TitleGlypicans shield the Wnt lipid moiety to enable signalling at a distance.
Journal, issue, pagesNature, Vol. 585, Page 85-90, Year 2020
Publish dateJan 16, 2020 (structure data deposition date)
AuthorsMcGough, I.J. / Vecchia, L. / Bishop, B. / Malinauskas, T. / Beckett, K. / Joshi, D. / O'Reilly, N. / Siebold, C. / Jones, E.Y. / Vincent, J.P.
External linksNature / PubMed:32699409
MethodsX-ray diffraction
Resolution2.21 Å
Structure data

PDB-6xtz:
Structure of Dally-like protein in complex with O-palmitoleoyl serine
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-O18:
O-palmitoleoyl serine

ChemComp-HOH:
WATER

Source
  • drosophila melanogaster (fruit fly)
KeywordsSIGNALING PROTEIN / Glypicans / GPI-anchored / Wnt / palmitoleate

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