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TitleTissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Journal, issue, pagesCell Rep, Vol. 32, Page 107922-107922, Year 2020
Publish dateOct 24, 2019 (structure data deposition date)
AuthorsKoirala, S. / Klein, J. / Zheng, Y. / Glenn, N.O. / Eisemann, T. / Fon Tacer, K. / Miller, D.J. / Kulak, O. / Lu, M. / Finkelstein, D.B. ...Koirala, S. / Klein, J. / Zheng, Y. / Glenn, N.O. / Eisemann, T. / Fon Tacer, K. / Miller, D.J. / Kulak, O. / Lu, M. / Finkelstein, D.B. / Neale, G. / Tillman, H. / Vogel, P. / Strand, D.W. / Lum, L. / Brautigam, C.A. / Pascal, J.M. / Clements, W.K. / Potts, P.R.
External linksCell Rep / PubMed:32698014
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-6urq:
Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/Transcription / TNKS / PAGE4 / tankyrase / PARP / cancer-testis antigen / Wnt signaling / Transferase-Transcription complex

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