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Structure paper

TitleThe structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
Journal, issue, pagesJ. Lipid Res., Vol. 61, Page 1347-1359, Year 2020
Publish dateApr 22, 2020 (structure data deposition date)
AuthorsLuz, J.G. / Beigneux, A.P. / Asamoto, D.K. / He, C. / Song, W. / Allan, C.M. / Morales, J. / Tu, Y. / Kwok, A. / Cottle, T. ...Luz, J.G. / Beigneux, A.P. / Asamoto, D.K. / He, C. / Song, W. / Allan, C.M. / Morales, J. / Tu, Y. / Kwok, A. / Cottle, T. / Meiyappan, M. / Fong, L.G. / Kim, J.E. / Ploug, M. / Young, S.G. / Birrane, G.
External linksJ. Lipid Res. / PubMed:32690595
MethodsX-ray diffraction
Resolution2.8 - 2.85 Å
Structure data

PDB-6wn4:
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-6wt3:
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / 5D2 / LIPOPROTEIN LIPASE

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