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TitlePromutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.
Journal, issue, pagesBiochem. J., Vol. 477, Page 2859-2871, Year 2020
Publish dateJan 7, 2020 (structure data deposition date)
AuthorsJung, H. / Lee, S.
External linksBiochem. J. / PubMed:32686822
MethodsX-ray diffraction
Resolution2.84 - 3.08 Å
Structure data

PDB-6vg6:
Crystal structure of DPO4 with 8-oxoadenine (oxoA) and dGTP*
Method: X-RAY DIFFRACTION / Resolution: 3.08 Å

PDB-6vgm:
Crystal structure of DPO4 with 8-oxoadenine (oxoA) and dTTP*
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Chemicals

ChemComp-XG4:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-1FZ:
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine

Source
  • saccharolobus solfataricus (archaea)
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / Y-family DNA polymerase / Translesion synthesis / TRANSFERASE / TRANSFERASE-DNA complex / DPO4

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