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Structure paper

TitleMolecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation.
Journal, issue, pagesDNA Repair (Amst), Vol. 94, Page 102899-102899, Year 2020
Publish dateDec 6, 2019 (structure data deposition date)
AuthorsYang, X. / Ma, Y. / Li, Y. / Dong, Y. / Yu, L.L. / Wang, H. / Guo, L. / Wu, C. / Yu, X. / Liu, X.
External linksDNA Repair (Amst) / PubMed:32683309
MethodsX-ray diffraction
Resolution1.999 Å
Structure data

PDB-6lh4:
Crystal structural of MacroD1-ADPr complex
Method: X-RAY DIFFRACTION / Resolution: 1.999 Å

Chemicals

ChemComp-AR6:
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / MacroD1 / ADPR / catalysis / DNA repair

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