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TitleBiodistribution PET/CT Study of Hemoglobin-DFO-89Zr Complex in Healthy and Lung Tumor-Bearing Mice.
Journal, issue, pagesInt J Mol Sci, Vol. 21, Year 2020
Publish dateSep 5, 2018 (structure data deposition date)
AuthorsKiraga, L. / Cerutti, G. / Braniewska, A. / Strzemecki, D. / Sas, Z. / Boffi, A. / Savino, C. / Montemiglio, L.C. / Turnham, D. / Seaton, G. ...Kiraga, L. / Cerutti, G. / Braniewska, A. / Strzemecki, D. / Sas, Z. / Boffi, A. / Savino, C. / Montemiglio, L.C. / Turnham, D. / Seaton, G. / Bonamore, A. / Clarkson, R. / Dabkowski, A.M. / Paisey, S.J. / Taciak, B. / Kucharzewska, P. / Rygiel, T.P. / Krol, M.
External linksInt J Mol Sci / PubMed:32679799
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-6hk2:
Crystal structure of ferric R-state human methemoglobin bound to maleimide-deferoxamine bifunctional chelator (DFO)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-OXY:
OXYGEN MOLECULE

ChemComp-SO4:
SULFATE ION

ChemComp-G7Z:
3-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]-~{N}-methyl-propanamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXYGEN TRANSPORT / DFO / COMPLEX / BETA CYS93

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