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TitleDirect readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 18439-18447, Year 2020
Publish dateAug 1, 2019 (structure data deposition date)
AuthorsRen, W. / Fan, H. / Grimm, S.A. / Guo, Y. / Kim, J.J. / Yin, J. / Li, L. / Petell, C.J. / Tan, X.F. / Zhang, Z.M. ...Ren, W. / Fan, H. / Grimm, S.A. / Guo, Y. / Kim, J.J. / Yin, J. / Li, L. / Petell, C.J. / Tan, X.F. / Zhang, Z.M. / Coan, J.P. / Gao, L. / Cai, L. / Detrick, B. / Cetin, B. / Cui, Q. / Strahl, B.D. / Gozani, O. / Wang, Y. / Miller, K.M. / O'Leary, S.E. / Wade, P.A. / Patel, D.J. / Wang, G.G. / Song, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:32675241
MethodsX-ray diffraction
Resolution3.01 Å
Structure data

PDB-6pzv:
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsDNA BINDING PROTEIN / DNA methylation / DNA methyltransferase 1 / Histone modification / Ubiquitylation

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