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Structure paper

TitleThe discovery of a new antibody for BRIL-fused GPCR structure determination.
Journal, issue, pagesSci Rep, Vol. 10, Page 11669-11669, Year 2020
Publish dateMay 21, 2020 (structure data deposition date)
AuthorsMiyagi, H. / Asada, H. / Suzuki, M. / Takahashi, Y. / Yasunaga, M. / Suno, C. / Iwata, S. / Saito, J.I.
External linksSci Rep / PubMed:32669569
MethodsX-ray diffraction
Resolution3 - 3.4 Å
Structure data

PDB-7c61:
Crystal structure of 5-HT1B-BRIL and SRP2070_Fab complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7c6a:
Crystal structure of AT2R-BRIL and SRP2070_Fab complex
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-ERM:
Ergotamine / neurotransmitter, alkaloid*YM

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
  • escherichia coli (E. coli)
KeywordsSIGNALING PROTEIN / GPCR / BRIL / Crystallization / Antibody

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