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TitleInhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Journal, issue, pagesAcs Chem. Biol., Vol. 15, Page 2041-2047, Year 2020
Publish dateAug 21, 2019 (structure data deposition date)
AuthorsLeandro, J. / Khamrui, S. / Wang, H. / Suebsuwong, C. / Nemeria, N.S. / Huynh, K. / Moustakim, M. / Secor, C. / Wang, M. / Dodatko, T. ...Leandro, J. / Khamrui, S. / Wang, H. / Suebsuwong, C. / Nemeria, N.S. / Huynh, K. / Moustakim, M. / Secor, C. / Wang, M. / Dodatko, T. / Stauffer, B. / Wilson, C.G. / Yu, C. / Arkin, M.R. / Jordan, F. / Sanchez, R. / DeVita, R.J. / Lazarus, M.B. / Houten, S.M.
External linksAcs Chem. Biol. / PubMed:32633484
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-6u3j:
Structure of the 2-oxoadipate dehydrogenase DHTKD1
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-TPP:
THIAMINE DIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / lysine metabolism mitochondrial dehydrogenase

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