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Structure paper

TitleArchitecture and functional dynamics of the pentafunctional AROM complex.
Journal, issue, pagesNat. Chem. Biol., Vol. 16, Page 973-978, Year 2020
Publish dateSep 25, 2018 (structure data deposition date)
AuthorsArora Veraszto, H. / Logotheti, M. / Albrecht, R. / Leitner, A. / Zhu, H. / Hartmann, M.D.
External linksNat. Chem. Biol. / PubMed:32632294
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-6hqv:
Pentafunctional AROM Complex from Chaetomium thermophilum
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-ZN:
Unknown entry

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-PO4:
PHOSPHATE ION

ChemComp-3DS:
(4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid

ChemComp-SKM:
(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID

Source
  • chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719) (fungus)
KeywordsBIOSYNTHETIC PROTEIN / Multifunctional Enzyme / Shikimate Pathway / Aromatic Amino Acid Biosynthesis / 3-Dehydroquinate Synthase / 3-Dehydroquinate Dehydratase / Shikimate Dehydrogenase / Shikimate Kinase / 3-Phosphoshikimate 1-Carboxyvinyltransferase / 5-Enolpyruvylshikimate-3-Phosphate Synthase

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