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-Structure paper
| Title | Clinical targeting of HIV capsid protein with a long-acting small molecule. |
|---|---|
| Journal, issue, pages | Nature, Vol. 584, Page 614-618, Year 2020 |
| Publish date | Nov 22, 2019 (structure data deposition date) |
 Authors | Link, J.O. / Rhee, M.S. / Tse, W.C. / Zheng, J. / Somoza, J.R. / Rowe, W. / Begley, R. / Chiu, A. / Mulato, A. / Hansen, D. ...Link, J.O. / Rhee, M.S. / Tse, W.C. / Zheng, J. / Somoza, J.R. / Rowe, W. / Begley, R. / Chiu, A. / Mulato, A. / Hansen, D. / Singer, E. / Tsai, L.K. / Bam, R.A. / Chou, C.H. / Canales, E. / Brizgys, G. / Zhang, J.R. / Li, J. / Graupe, M. / Morganelli, P. / Liu, Q. / Wu, Q. / Halcomb, R.L. / Saito, R.D. / Schroeder, S.D. / Lazerwith, S.E. / Bondy, S. / Jin, D. / Hung, M. / Novikov, N. / Liu, X. / Villasenor, A.G. / Cannizzaro, C.E. / Hu, E.Y. / Anderson, R.L. / Appleby, T.C. / Lu, B. / Mwangi, J. / Liclican, A. / Niedziela-Majka, A. / Papalia, G.A. / Wong, M.H. / Leavitt, S.A. / Xu, Y. / Koditek, D. / Stepan, G.J. / Yu, H. / Pagratis, N. / Clancy, S. / Ahmadyar, S. / Cai, T.Z. / Sellers, S. / Wolckenhauer, S.A. / Ling, J. / Callebaut, C. / Margot, N. / Ram, R.R. / Liu, Y.P. / Hyland, R. / Sinclair, G.I. / Ruane, P.J. / Crofoot, G.E. / McDonald, C.K. / Brainard, D.M. / Lad, L. / Swaminathan, S. / Sundquist, W.I. / Sakowicz, R. / Chester, A.E. / Lee, W.E. / Daar, E.S. / Yant, S.R. / Cihlar, T. |
 External links | Nature / PubMed:32612233 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data |  PDB-6v2f: |
| Chemicals |  ChemComp-QNG:  ChemComp-HOH: |
| Source |
|
 Keywords | VIRAL PROTEIN / HIV capsid / capsid assembly accelerator / long-acting inhibitor / antiviral |
human immunodeficiency virus 1