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TitleSelective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Journal, issue, pagesCancer Cell, Vol. 38, Page 115-128.e9, Year 2020
Publish dateNov 30, 2018 (structure data deposition date)
AuthorsTang, Y. / Fang, G. / Guo, F. / Zhang, H. / Chen, X. / An, L. / Chen, M. / Zhou, L. / Wang, W. / Ye, T. ...Tang, Y. / Fang, G. / Guo, F. / Zhang, H. / Chen, X. / An, L. / Chen, M. / Zhou, L. / Wang, W. / Ye, T. / Nie, P. / Yu, H. / Lin, M. / Zhao, Y. / Lin, X. / Yuan, Z. / Jiao, S. / Zhou, Z.
External linksCancer Cell / PubMed:32589942
MethodsX-ray diffraction
Resolution3.33 Å
Structure data

PDB-6iur:
A phosphatase complex STRN3-PP2Aa
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

Chemicals

ChemComp-TME:
PROPANE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Phosphatase / Complex

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