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TitleUnique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 11602-11612, Year 2020
Publish dateAug 10, 2019 (structure data deposition date)
AuthorsYun, C.S. / Nishimoto, K. / Motoyama, T. / Shimizu, T. / Hino, T. / Dohmae, N. / Nagano, S. / Osada, H.
External linksJ. Biol. Chem. / PubMed:32565425
MethodsX-ray diffraction
Resolution1.68 Å
Structure data

PDB-6kog:
Ketosynthase domain in tenuazonic acid synthetase 1 (TAS1).
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • pyricularia oryzae 70-15 (fungus)
KeywordsBIOSYNTHETIC PROTEIN / Ketosynthase domain / cyclization / tetramic acid ring formation / NRPS-PKS hybrid enzyme / TOXIN

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