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-Structure paper
Title | A conformation-specific ON-switch for controlling CAR T cells with an orally available drug. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 117, Page 14926-14935, Year 2020 |
Publish date | Dec 20, 2018 (structure data deposition date) |
![]() | Zajc, C.U. / Dobersberger, M. / Schaffner, I. / Mlynek, G. / Puhringer, D. / Salzer, B. / Djinovic-Carugo, K. / Steinberger, P. / De Sousa Linhares, A. / Yang, N.J. ...Zajc, C.U. / Dobersberger, M. / Schaffner, I. / Mlynek, G. / Puhringer, D. / Salzer, B. / Djinovic-Carugo, K. / Steinberger, P. / De Sousa Linhares, A. / Yang, N.J. / Obinger, C. / Holter, W. / Traxlmayr, M.W. / Lehner, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | ![]() PDB-6qba: |
Chemicals | ![]() ChemComp-2T1: ![]() ChemComp-IMD: ![]() ChemComp-PEG: ![]() ChemComp-ZN: ![]() ChemComp-ACT: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSPORT PROTEIN / Lipocalin / RBP4 / Retinol binding protein |