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TitleAn Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals.
Journal, issue, pagesCell Chem Biol, Vol. 27, Page 1192-1198.e5, Year 2020
Publish dateJan 27, 2020 (structure data deposition date)
AuthorsMiller, S. / Aikawa, Y. / Sugiyama, A. / Nagai, Y. / Hara, A. / Oshima, T. / Amaike, K. / Kay, S.A. / Itami, K. / Hirota, T.
External linksCell Chem Biol / PubMed:32502390
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6lue:
Crystal structure of mouse Cryptochrome 1 in complex with compound KL201
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-EUL:
2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsCIRCADIAN CLOCK PROTEIN / Cryptochrome / CRY / circadian clock / KL201

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