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TitleCrystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease.
Journal, issue, pagesJ. Lipid Res., Vol. 61, Page 1192-1202, Year 2020
Publish dateDec 9, 2019 (structure data deposition date)
AuthorsRajamohan, F. / Reyes, A.R. / Tu, M. / Nedoma, N.L. / Hoth, L.R. / Schwaid, A.G. / Kurumbail, R.G. / Ward, J. / Han, S.
External linksJ. Lipid Res. / PubMed:32482718
MethodsX-ray diffraction
Resolution2.62 Å
Structure data

PDB-6v7n:
Crystal Structure of a human Lysosome Resident Glycoprotein, Lysosomal Acid Lipase, and its Implications in Cholesteryl Ester Storage Disease (CESD)
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Lysosomal acid lipase / Cholesteryl Ester Storage Disease

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