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TitleInhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 13499-13508, Year 2020
Publish dateSep 20, 2019 (structure data deposition date)
AuthorsMeng, B. / Lan, K. / Xie, J. / Lerner, R.A. / Wilson, I.A. / Yang, B.
External linksProc. Natl. Acad. Sci. USA / PubMed:32467165
MethodsX-ray diffraction
Resolution1.845 - 2.4 Å
Structure data

PDB-6kyz:
HRV14 3C in complex with single chain antibody YDF
Method: X-RAY DIFFRACTION / Resolution: 1.845 Å

PDB-6kz0:
HRV14 3C in complex with single chain antibody GGVV
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human rhinovirus 14
  • homo sapiens (human)
KeywordsVIRAL PROTEIN / protease / inhibitor / complex structure

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