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Structure paper

TitleHigh-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 12826-12835, Year 2020
Publish dateOct 8, 2019 (structure data deposition date)
AuthorsSim, M.J.W. / Lu, J. / Spencer, M. / Hopkins, F. / Tran, E. / Rosenberg, S.A. / Long, E.O. / Sun, P.D.
External linksProc. Natl. Acad. Sci. USA / PubMed:32461371
MethodsX-ray diffraction
Resolution1.88 - 3.5 Å
Structure data

PDB-6uli:
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-6ulk:
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6uln:
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-6ulr:
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6uon:
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HLA-C Neoantigen KRAS

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