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Structure paper

TitleAlgal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 12799-12805, Year 2020
Publish dateJan 22, 2020 (structure data deposition date)
AuthorsChekan, J.R. / McKinnie, S.M.K. / Noel, J.P. / Moore, B.S.
External linksProc. Natl. Acad. Sci. USA / PubMed:32457155
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-6vkz:
Crystal Structure of the N-prenyltransferase DabA in Complex with GSPP and Mg2+
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6vl0:
Crystal Structure of the N-prenyltransferase DabA in Complex with GSPP and Mn2+
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6vl1:
Crystal Structure of the N-prenyltransferase DabA in Complex with NGG and Mg2+
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GST:
GERANYL S-THIOLODIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-R1V:
N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-L-glutamic acid

Source
  • pseudo-nitzschia multiseries (Diatom)
KeywordsTRANSFERASE / prenyltransferase / terpene cyclase

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