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TitleAncient MAPK ERK7 is regulated by an unusual inhibitory scaffold required forToxoplasmaapical complex biogenesis.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 12164-12173, Year 2020
Publish dateDec 4, 2019 (structure data deposition date)
AuthorsBack, P.S. / O'Shaughnessy, W.J. / Moon, A.S. / Dewangan, P.S. / Hu, X. / Sha, J. / Wohlschlegel, J.A. / Bradley, P.J. / Reese, M.L.
External linksProc. Natl. Acad. Sci. USA / PubMed:32409604
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6v6a:
Inhibitory scaffolding of the ancient MAPK, ERK7
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • toxoplasma gondii (eukaryote)
KeywordsSIGNALING PROTEIN / protein kinase / MAPK / intrinsically-disordered protein / scaffold

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