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TitleComputational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.
Journal, issue, pagesNat Commun, Vol. 11, Page 2330-2330, Year 2020
Publish dateAug 13, 2019 (structure data deposition date)
AuthorsFroning, K. / Maguire, J. / Sereno, A. / Huang, F. / Chang, S. / Weichert, K. / Frommelt, A.J. / Dong, J. / Wu, X. / Austin, H. ...Froning, K. / Maguire, J. / Sereno, A. / Huang, F. / Chang, S. / Weichert, K. / Frommelt, A.J. / Dong, J. / Wu, X. / Austin, H. / Conner, E.M. / Fitchett, J.R. / Heng, A.R. / Balasubramaniam, D. / Hilgers, M.T. / Kuhlman, B. / Demarest, S.J.
External linksNat Commun / PubMed:32393818
MethodsX-ray diffraction
Resolution1.76 Å
Structure data

PDB-6u07:
Computational Stabilization of T Cell Receptor Constant Domains
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / T cell receptor / TCR constant domains

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