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Structure paper

TitleUbiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Journal, issue, pagesNucleic Acids Res., Vol. 48, Page 6310-6325, Year 2020
Publish dateAug 1, 2019 (structure data deposition date)
AuthorsSchellenberg, M.J. / Appel, C.D. / Riccio, A.A. / Butler, L.R. / Krahn, J.M. / Liebermann, J.A. / Cortes-Ledesma, F. / Williams, R.S.
External linksNucleic Acids Res. / PubMed:32356875
MethodsX-ray diffraction
Resolution0.85 - 0.851 Å
Structure data

PDB-6q00:
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1
Method: X-RAY DIFFRACTION / Resolution: 0.85 Å

PDB-6q01:
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2
Method: X-RAY DIFFRACTION / Resolution: 0.851 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-BEZ:
BENZOIC ACID

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsSIGNALING PROTEIN/HYDROLASE / TDP2 / DNA Damage Response / Cell Signaling / post-translational modification / Topoisomerase 2 / SIGNALING PROTEIN / SIGNALING PROTEIN-HYDROLASE complex

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