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-Structure paper
Title | Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 5488-5500, Year 2020 |
Publish date | Sep 15, 2019 (structure data deposition date) |
Authors | Sharma, U. / Cozier, G.E. / Sturrock, E.D. / Acharya, K.R. |
External links | J. Med. Chem. / PubMed:32337993 |
Methods | X-ray diffraction |
Resolution | 1.75 - 2.65 Å |
Structure data | PDB-6suk: PDB-6svy: PDB-6xvp: |
Chemicals | ChemComp-ZN: ChemComp-NAG: ChemComp-FT8: ChemComp-PEG: ChemComp-EDO: ChemComp-HOH: ChemComp-D0W: ChemComp-D0Z: |
Source |
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Keywords | HYDROLASE / metallopeptidase / Neural endopeptidase / Omapatrilat / Sampatrilat-ASP / Sampatrilat |