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-Structure paper
| Title | Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 63, Page 5488-5500, Year 2020 |
| Publish date | Sep 15, 2019 (structure data deposition date) |
Authors | Sharma, U. / Cozier, G.E. / Sturrock, E.D. / Acharya, K.R. |
External links | J. Med. Chem. / PubMed:32337993 |
| Methods | X-ray diffraction |
| Resolution | 1.75 - 2.65 Å |
| Structure data | ![]() PDB-6suk: ![]() PDB-6svy: ![]() PDB-6xvp: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-NAG: ![]() ChemComp-FT8: ![]() ChemComp-PEG: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-D0W: ![]() ChemComp-D0Z: |
| Source |
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Keywords | HYDROLASE / metallopeptidase / Neural endopeptidase / Omapatrilat / Sampatrilat-ASP / Sampatrilat |
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homo sapiens (human)
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