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Structure paper

TitleDual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Journal, issue, pagesStructure, Vol. 28, Page 747-759.e3, Year 2020
Publish dateJan 13, 2020 (structure data deposition date)
AuthorsGogl, G. / Jane, P. / Caillet-Saguy, C. / Kostmann, C. / Bich, G. / Cousido-Siah, A. / Nyitray, L. / Vincentelli, R. / Wolff, N. / Nomine, Y. ...Gogl, G. / Jane, P. / Caillet-Saguy, C. / Kostmann, C. / Bich, G. / Cousido-Siah, A. / Nyitray, L. / Vincentelli, R. / Wolff, N. / Nomine, Y. / Sluchanko, N.N. / Trave, G.
External linksStructure / PubMed:32294469
MethodsX-ray diffraction
Resolution2.3 - 2.8 Å
Structure data

PDB-6twq:
MAGI1_2 complexed with a 16E6 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-6twu:
MAGI1_2 complexed with a phosphomimetic 16E6 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-6twx:
MAGI1_2 complexed with a phosphorylated 16E6 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6twy:
MAGI1_2 complexed with a phosphomimetic RSK1 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6twz:
14-3-3 sigma complexed with a phosphorylated 16E6 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-TAR:
D(-)-TARTARIC ACID

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • homo sapiens (human)
  • human papillomavirus type 16
KeywordsPEPTIDE BINDING PROTEIN / phosphorylation / motif / PDZ domain / 14-3-3 protein

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