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-Structure paper
Title | Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1). |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 11, Page 550-557, Year 2020 |
Publish date | Dec 3, 2019 (structure data deposition date) |
Authors | White, C. / McGowan, M.A. / Zhou, H. / Sciammetta, N. / Fradera, X. / Lim, J. / Joshi, E.M. / Andrews, C. / Nickbarg, E.B. / Cowley, P. ...White, C. / McGowan, M.A. / Zhou, H. / Sciammetta, N. / Fradera, X. / Lim, J. / Joshi, E.M. / Andrews, C. / Nickbarg, E.B. / Cowley, P. / Trewick, S. / Augustin, M. / von Koenig, K. / Lesburg, C.A. / Otte, K. / Knemeyer, I. / Woo, H. / Yu, W. / Cheng, M. / Spacciapoli, P. / Geda, P. / Song, X. / Smotrov, N. / Curran, P. / Heo, M.R. / Abeywickrema, P. / Miller, J.R. / Bennett, D.J. / Han, Y. |
External links | Acs Med. Chem. Lett. / PubMed:32292563 |
Methods | X-ray diffraction |
Resolution | 1.78 Å |
Structure data | PDB-6v52: |
Chemicals | ChemComp-QPV: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / INDOLEAMINE DIOXYGENASE / HEME / INHIBITOR |