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Structure paper

TitleMutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.
Journal, issue, pagesNucleic Acids Res., Vol. 48, Page 5119-5134, Year 2020
Publish dateJun 30, 2019 (structure data deposition date)
AuthorsKoag, M.C. / Jung, H. / Lee, S.
External linksNucleic Acids Res. / PubMed:32282906
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6plc:
Structure of human DNA polymerase eta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-XG4:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN/DNA / Human DNA polymerase / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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