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-Structure paper
Title | Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 117, Page 8468-8475, Year 2020 |
Publish date | Nov 7, 2019 (structure data deposition date) |
Authors | Petrie, E.J. / Birkinshaw, R.W. / Koide, A. / Denbaum, E. / Hildebrand, J.M. / Garnish, S.E. / Davies, K.A. / Sandow, J.J. / Samson, A.L. / Gavin, X. ...Petrie, E.J. / Birkinshaw, R.W. / Koide, A. / Denbaum, E. / Hildebrand, J.M. / Garnish, S.E. / Davies, K.A. / Sandow, J.J. / Samson, A.L. / Gavin, X. / Fitzgibbon, C. / Young, S.N. / Hennessy, P.J. / Smith, P.P.C. / Webb, A.I. / Czabotar, P.E. / Koide, S. / Murphy, J.M. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:32234780 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-6ux8: |
Chemicals | ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / Protein interactions / cell death / RIPK3 / programmed necrosis / protein engineering |