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TitleActivation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6.
Journal, issue, pagesNat Commun, Vol. 11, Page 1596-1596, Year 2020
Publish dateJan 7, 2020 (structure data deposition date)
AuthorsGarcia-Doval, C. / Schwede, F. / Berk, C. / Rostol, J.T. / Niewoehner, O. / Tejero, O. / Hall, J. / Marraffini, L.A. / Jinek, M.
External linksNat Commun / PubMed:32221291
MethodsX-ray diffraction
Resolution2.42 Å
Structure data

PDB-6tug:
Enterococcus italicus Csm6 bound to cyclic hexa-2'-fluoro-hexa-dAMP
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

Chemicals

ChemComp-AF2:
2'-deoxy-2'-fluoroadenosine 5'-(dihydrogen phosphate)

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • enterococcus italicus (strain dsm 15952 / lmg 22039 / tp 1.5) (bacteria)
KeywordsRNA BINDING PROTEIN / CRISPR / cyclic oligoadenylate / RNase / nuclease

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