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-Structure paper
Title | Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Year 2020 |
Publish date | Apr 4, 2018 (structure data deposition date) |
Authors | Bhatt, A.P. / Pellock, S.J. / Biernat, K.A. / Walton, W.G. / Wallace, B.D. / Creekmore, B.C. / Letertre, M.M. / Swann, J.R. / Wilson, I.D. / Roques, J.R. ...Bhatt, A.P. / Pellock, S.J. / Biernat, K.A. / Walton, W.G. / Wallace, B.D. / Creekmore, B.C. / Letertre, M.M. / Swann, J.R. / Wilson, I.D. / Roques, J.R. / Darr, D.B. / Bailey, S.T. / Montgomery, S.A. / Roach, J.M. / Azcarate-Peril, M.A. / Sartor, R.B. / Gharaibeh, R.Z. / Bultman, S.J. / Redinbo, M.R. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:32170007 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-6cxs: |
Chemicals | ChemComp-FJV: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE-INHIBITOR complex / HYDROLASE-HYDROLASE INHIBITOR complex |